慜怹弫惈昦曄

戞2斉

戞3斉偍傛傃2004擭斉

戞2斉偱偼丄堎宍惉偲忋旂撪娻偑椙惈忋旂惈庮釃偲埆惈忋旂惈庮釃偲偼暿偵丄暘椶偝傟偰偄傑偟偨丅 戞3斉偱偼丄滸暯忋旂娻偺precursor偲偟偰堎宍惉偲忋旂撪娻傪偁偘偰偄傑偡丅峏偵丄嵶婥娗巟攛朎忋旂娻偺precursor偲偟偰丄堎宆態庮條夁宍惉傪偁偘偰偄傑偡丅傑偨丄攛偺恄宱撪暘斿嵶朎偑夁宍惉傪偍偙偟偨傕偺偲偟偰丄傃傑傫惈摿敪惈攛恄宱撪暘斿嵶朎夁宍惉 傪偁偘偰偄傑偡丅

堎宍惉偲忋旂撪娻
嵍偵堎宍惉傪帵偟傑偡丅堎宍惉偼忋旂撪偵堎宆嵶朎偑弌尰偟偰偄傞傕偺偱丄嵶朎堎宆傗峔憿堎宆偐傜掱搙傪寉搙丄拞摍搙丄崅搙偵傢偗偰偄傑偡丅堎宍惉偵偼忋旂撪偵栄嵶寣娗乮栴報乯傪擣傔傞偙偲偑偁傝傑偡丅堎宍惉偵偍偄偰偼栄嵶寣娗偺怴惗偑婲偒偰偍傝丄楢懕愗曅傪娤嶡偡傞偙偲偵傛傝丄幹峴偟偨婎掙枌捈壓偺栄嵶寣娗偑丄昗杮偺愗傟曽偵傛傝忋旂偺拞偵懚嵼偡傞傛偆偵尒偊傞偙偲偑傢偐傝傑偡[1]丅 塃偺幨恀偼丄嵍偺徢椺傪侾擭娫follow up偟偨偲偙傠丄滸暯忋旂娻偑敪惗偟丄庤弍偵傛傝揈弌偟偨昗杮偱偡丅堎宆偺傛傝崅搙側嵶朎偵傛傝丄忋旂偺慡憌偑抲姺偝傟偰偄傑偡偑丄婎掙枌傪挻偊偰怹弫傪偟偰偄側偄偨傔丄忋旂撪娻偲恌抐偟傑偡丅

堎宆態庮條夁宍惉

堎宆態庮條夁宍惉偺戝偒偝偼丄5mm埲壓偱偡偑丄傑傟偵10mm埲忋偺偙偲傕偁傝傑偡丅嵶朎偺宍偼丄墌宍丄棫曽宍丄掅墌拰宍丄儁僌忬偱偡丅慄栄忋旂嵶朎傗擲塼傪擖傟傞嵶朎偼尒傜傟傑偣傫丅 堎宆偺寉搙側嵶朎偑旕楢懕揑偵攛朎暻傪偍偍偭偰偄傑偡丅

傃傑傫惈摿敪惈攛恄宱撪暘斿嵶朎夁宍惉
 嵶婥娗巟偺慡廃惈偵丄慄栄墌拰忋旂偺婎掙枌懁偵丄恄宱撪暘斿嵶朎偑憹惗偟偨傝丄嵶婥娗巟忋旂撪傗丄廃埻偵朎憙傪宍惉偟傑偡丅

栤戣揰
滸暯忋旂娻偺慜怹弫惈昦曄偲偟偰丄堎宍惉偲忋旂撪娻傪偁偘偰偄傑偡丅嵶婥娗巟攛朎忋旂娻偺慜怹弫惈昦曄偲偟偰丄堎宆態庮條夁宍惉傪偁偘偰偄傑偡丅屻偱丄愢柧偟傑偡偑丄態娻偺垷宆偱偁傞嵶婥娗巟攛朎忋旂娻傕怹弫偺側偄傕偺偲掕媊偝傟偰偄傑偡丅偟偐偟丄慜怹弫惈昦曄偵偼娷傑傟偰偄傑偣傫丅摑堦惈偺柺偐傜丄栤戣偑偁傞偲巚偄傑偡丅

堷梡暥專

  1. Hiroshima K, Iyoda A, Shibuya K, Hoshino H, Haga Y, Toyozaki T, Shiba M, Baba M, Fujisawa T, Ohwada H. Evidence of neoangiogenesis and an increase in the number of proliferating cells within the bronchial epithelium of smokers. Cancer 95, 1539-1545, 2002
  2. Nakatani Y, Kitamura H, Inayama Y, Kamijo S, Nagashima Y, Shimoyama K, Nakamura N, Sano J, Ogawa N, Shibagaki T, Resl M, Mark EJ. Pulmonary adenocarcinomas of the fetal lung type: a clinicopathologic study indicating differences in histology, epidemiology, and natural history of low-grade and high-grade forms. Am. J. Surg. Pathol. 22, 399-411, 1998
  3. Nakatani Y, Masudo K, Miyagi Y, Inayama Y, Kawano N, Tanaka Y, Kato K, Ito T, Kitamura H, Nagashima Y, Yamanaka S, Nakamura N, Sano J, Ogawa N, Ishiwa N, Notohara K, Resl M, Mark EJ. Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morules. Mod. Pathol. 15, 617-24, 2002
  4. Iyoda A, Hiroshima K, Toyozaki T, Tsukamoto Y, Haga Y, Fujisawa T, Ohwada H. Clear cell adenocarcinoma with endobronchial polypoid growth. Pathol. Int. 50, 979-983, 2000
  5. Hiroshima K, Shibuya K, Shimamura F, Toyozaki T, HagaY, Ohwada H, Iyoda A, Sekine Y, Iizasa T, Fujisawa T. Pulmonary large cell carcinoma with rhabdoid phenotype. Ultrastruct. Pathol. 27, 55-59, 2003
  6. Hiroshima K, Abe S, Ebihara Y, Ogura S, Kikui M, Kodama T, Komatsu H, Saito Y, Sagawa M, Sato M, Tagawa Y, Nakamura S, Nakayama T, Baba M, Hanzawa S, Hirano T, Horai T. Cytological characteristics of pulmonary large cell neuroendocrine carcinoma. Lung Cancer 48, 331-7, 2005
  7. Iyoda A, Hiroshima K, Toyozaki T, Haga Y, Fujisawa T, Ohwada H. Clinical characterization of pulmonary large cell neuroendocrine carcinoma and large cell carcinoma with neuroendocrine morphology. Cancer 91, 1992-2000, 2001
  8. Iyoda A, Hiroshima K, Baba M, Saitoh Y, Ohwada H, Fujisawa T. Pulmonary large cell carcinomas with neuroendocrine features are high-grade neuroendocrine tumors. Ann. Thorac. Surg. 73, 1049-1054, 2002
  9. Iyoda A, Hiroshima K, Toyozaki T, Haga Y, Baba M, Fujisawa T, Ohwada H. Adjuvant chemotherapy for large cell carcinoma with neuroendocrine features. Cancer 92, 1108-1112, 2001
  10. Travis WD, Gal AA, Colby TV, Klimstra DS, Falk R, Koss MN. Reproducibility of neuroendocrine lung tumor classification. Hum Pathol. 29, 272-279, 1998
  11. Hiroshima K, Ishibashi M, Ohwada H, Kawano Y, Mizutani F, Hayashi Y. A case of adenocarcinoma of the lung with a spindle cell component. Acta Pathol. Jpn. 42, 841-846, 1992
  12. Nakatani Y, Miyagi Y, Takemura T, Oka T, Yokoi T, Takagi M, Yokoyama S, Kashima K, Hara K, Yamada T, Nozawa A, Inayama Y, Sakamoto K, Ogawa N, Kitamura H, Resl M, Cho SH, Koss MN, Mark EJ. Aberrant nuclear/cytoplasmic localization and gene mutation of beta-catenin in classic pulmonary blastoma: beta-catenin immunostaining is useful for distinguishing between classic pulmonary blastoma and a blastomatoid variant of carcinosarcoma. Am. J. Surg. Pathol. 28, 921-7, 2004

杮峞偵宖嵹偝傟偰偄傞尠旝嬀幨恀側偳偼丄屄恖偱巊梡偝傟傞応崌偼丄偛帺桼偵僟僂儞儘乕僪偟偰偄偨偩偄偨寢峔偱偡丅偨偩偟丄岞昞偝傟傞応崌傗儕儞僋傪偝傟傞応崌偼丄弌揟傪柧傜偐偵偟偰偔偩偝偄丅

戞45夞擔杮屇媧婍妛夛妛弍島墘夛丂嫵堢島墘丂(2005.4.15丂墬枊挘)丂傛傝

搶嫗彈巕堛壢戝妛敧愮戙堛椕僙儞僞乕昦棟恌抐壢丂淎搰寬嶰